學歷
學校 系所 學位
國立成功大學 基礎醫學研究所 博士
經歷
期間 單位 部門 職稱
輔仁大學 學術特聘教授
輔仁大學 研發長
輔仁大學 基礎醫學研究所 所長
英國倫敦大學 博士後研究
國立成功大學 博士後研究
專長
電生理學
神經科學
神經藥理學
學術著作
期刊論文
期間 內容
期刊論文 (2021至今)
1. Lu CW, Lin TY, Pan WJ, Chang YY, Chiu KM, Lee MY, Wang SJ*. (2025 Jul 31) Casticin inhibits the release of synaptic vesicular glutamate from rat hippocampal nerve terminals. Neurochem Int.:106025.
2. Huang CF, Lin TK, Chang CC, Lee MY, Lu CY, Hung CF*, Wang SJ*. (2025 May 22) Birch Sap Preserves Memory Function in Rats by Enhancing Cerebral Blood Flow and Modulating the Presynaptic Glutamatergic System in the Hippocampus. Int J Mol Sci. 26(11):5009.
3. Chang Y, Pan WJ, Wang SJ*. (2025 Jul 5) Epigoitrin decreases synaptosomal glutamate release and protects neurons from glutamate excitotoxicity in rats. Eur J Pharmacol. 998:177654.
4. Lu CW, Lin TY, Pan WJ, Chiu KM, Lee MY, Wang SJ*. (2025 Apr 14) Cynarin protects against seizures and neuronal death in a rat model of kainic acid-induced seizures. Food Funct. 16(8):3048-3063.
5. Lu CW, Lin TY, Yeh KC, Hsieh PW, Chiu KM, Lee MY, Wang SJ*. (2025 May) Reduction in presynaptic glutamate release and the prevention of glutamate excitotoxicity by lupeol in rats. Neurochem Int. 185:105951.
6. Lin TK, Pai MS, Yeh KC, Hung CF*, Wang SJ*. (2025 Feb) Hydrogen inhalation exerts anti-seizure effects by preventing oxidative stress and inflammation in the hippocampus in a rat model of kainic acid-induced seizures. Neurochem Int. 183:105925.
7. Lu CW, Lin TY, Chang YY, Chiu KM, Lee MY, Wang SJ*. (2024) Albiflorin Decreases Glutamate Release from Rat Cerebral Cortex Nerve Terminals (Synaptosomes) through Depressing P/Q-Type Calcium Channels and Protein Kinase A Activity. Int J Mol Sci. 25(16):8846.
8. Chi-Feng Hung, Wei-Che Chiu, Jia-Cih Chen, Wu-Chang Chuang, Su-Jane Wang*. (2024) NRICM101 prevents kainic acid-induced seizures in rats by modulating neuroinflammation and the glutamatergic system. International Immunopharmacology 140:112842.
9. Chang Y, Chen YJ, Wang SJ*. (2024 Jun 13) Sodium Houttuyfonate Prevents Seizures and Neuronal Cell Loss by Maintaining Glutamatergic System Stability in Male Rats with Kainic Acid-Induced Seizures. Biomedicines 12(6):1312.
10. Lu CW, Lin TY, Chiu KM, Lee MY, Wang SJ*. (2024 May 16) Gypenoside XVII Reduces Synaptic Glutamate Release and Protects against Excitotoxic Injury in Rats. Biomolecules 14(5):589.
11. Lee MY, Lin TY, Chang YY, Chiu KM*, Wang SJ*. (2024 Feb 22) Phillygenin Suppresses Glutamate Exocytosis in Rat Cerebrocortical Nerve Terminals (Synaptosomes) through the Inhibition of Cav2.2 Calcium Channels. Biomedicines 12(3):495.
12. Lin TK, Yeh KC, Pai MS, Hsieh PW, Wang SJ*. (2024 Jan 15) Ursolic acid inhibits the synaptic release of glutamate and prevents glutamate excitotoxicity in rats. Eur J Pharmacol. 963:176280.
13. Pai MS, Wang KC, Yeh KC, Wang SJ*. (2023 Dec) Stabilization of mitochondrial function by chlorogenic acid protects against kainic acid-induced seizures and neuronal cell death in rats. Eur J Pharmacol. 961:176197.
14. Lu CW, Lin TY, Hsieh PW, Chiu KM, Lee MY, Wang SJ*. (2023 May) Cynarin, a caffeoylquinic acid derivative in artichoke, inhibits exocytotic glutamate release from rat cortical nerve terminals (synaptosomes). Neurochem Int. 167:105537.
15. Hsu SK, Lu CW, Chiu KM, Lee MY, Lin TY*, Wang SJ*. (2023 Jul) Mangiferin depresses vesicular glutamate release in synaptosomes from the rat cerebral cortex by decreasing synapsin I phosphorylation. Eur J Pharmacol. 950:175772.
16. Chiu KM, Lee MY, Lu CW*, Lin TY*, Wang SJ*. (2023 Jan) Plantainoside D reduces depolarization-evoked glutamate release from rat cerebral cortical synaptosomes. Molecules, 28, 1313.
17. Lu CW, Wu CC, Chiu KM, Lee MY, Lin TY*, Wang SJ*. (2022 Nov) Inhibition of synaptic glutamate exocytosis and prevention of glutamate neurotoxicity by eupatilin from Artemisia argyi in the rat cortex. Int J Mol Sci. 23(21):13406.
18. Chang A, Chang Y, Wang SJ*. (2022 Oct) Rutin prevents seizures in kainic acid-treated rats: evidence of glutamate levels, inflammation and neuronal loss modulation. Food Funct.13(20):10401-10414.
19. Lu CW, Yeh KC, Chiu KM, Lee MY, Lin TY*, Wang SJ*. (2022 Aug) The effect of isosaponarin derived from Wasabi leaves on glutamate release in rat synaptosomes and its underlying mechanism. Int J Mol Sci 23(15):8752.
20. Chiu KM, Lin TY, Lee MY, Lu CW, Wang SJ*. (2022 Jul) Lappaconitine inhibits glutamate release from rat cerebrocortical nerve terminals by suppressing Ca2+ influx and protein kinase A cascade. Neurotoxicology 91:218-227.
21. Hsieh TY, Chang Y, Wang SJ*. (2022 Apr) Piperine provides neuroprotection against kainic acid-induced neurotoxicity via maintaining NGF signalling pathway. Molecules. 27(9):2638.
22. Jean WH, Huang CT, Hsu JH, Chiu KM, Lee MY, Shieh JS, Lin TY*, Wang SJ*. (2022 May) Anticonvulsive and neuroprotective effects of eupafolin in rats are associated with the inhibition of glutamate overexcitation and upregulation of the wnt/β-catenin signaling pathway. ACS Chem Neurosci 13(10):1594-1603.
23. Lin TY, Hung CY, Chiu KM, Lee MY, Lu CW*, Wang SJ*. (2022 Apr) Neferine, an alkaloid from lotus seed embryos, exerts antiseizure and neuroprotective effects in a kainic acid-induced seizure model in rats. Int J Mol Sci 23(8):4130.
24. Yeh KC, Hung CF, Lee HL, Hsieh TY, Wang SJ*. (2022 Mar) Soybean meal extract preserves memory ability by increasing presynaptic function and modulating gut microbiota in rats. Mol Neurobiol 59(3):1649-1664.
25. Lu CW, Lin CJ, Hsieh PW, Chiu KM, Lee MY, Lin TY*, Wang SJ*. (2022 Feb) An anthranilate derivative inhibits glutamate release and glutamate excitotoxicity in rats. Int J Mol Sci 23(5):2641.
26. Lin TK, Hung CF, Weng JR, Hsieh TY, Wang SJ*. (2022 Feb) Kaempferol 3-rhamnoside on glutamate release from rat cerebrocortical nerve terminals involves P/Q-Type Ca2+ channel and Ca2+/calmodulin-dependent protein kinase II-dependent pathway suppression. Molecules 27(4):1342.
27. Lin TY, Chen IY, Lee MY, Lu CW, Chiu KM*, Wang SJ*. (2022 Jan) Inhibition of glutamate release from rat cortical nerve terminals by dehydrocorydaline, an alkaloid from Corydalis yanhusuo. Molecules 27(3):960.
28. Lu CW, Huang YC, Chiu KM, Lee MY, Lin TY*, Wang SJ*. (2021 Nov) Enmein decreases synaptic glutamate release and protects against kainic acid-induced brain injury in rats. Int J Mol Sci 22(23):12966.
29. Hung YC, Kuo YH, Hsieh PW, Hsieh TY, Kuo JR, Wang SJ*. (2021 Oct) Chlorogenic acid decreases glutamate release from rat cortical nerve terminals by P/Q-Type Ca2+ channel suppression: a possible neuroprotective mechanism. Int J Mol Sci 22(21):11447.
30. Lin TY, Lu CW, Hsieh PW, Chiu KM, Lee MY, Wang SJ*. (2021 Oct) Natural product isoliquiritigenin activates GABAB receptors to decrease voltage-gate Ca2+ channels and glutamate release in rat cerebrocortical nerve terminals. Biomolecules 18;11(10):1537.
31. Chang A, Hung CF, Hsieh PW, Ko HH, Wang SJ*. (2021 Nov) Eupafolin suppresses P/Q-Type Ca2+ channels to inhibit Ca2+/calmodulin-dependent protein kinase II and glutamate release at rat cerebrocortical nerve terminals. Biomol Ther (Seoul). 29(6):630-636.
32. Wang CC, Hsieh PW, Kuo JR, Wang SJ*. (2021 Jul) Rosmarinic acid, a bioactive phenolic compound, inhibits glutamate release from rat cerebrocortical synaptosomes through GABAA receptor activation. Biomolecules 11(7):1029.
33. Lu CW, Lin TY, Huang SK, Chiu KM, Lee MY, Huang JH, Wang SJ*. (2021 Jul) Inhibition of glutamatergic transmission and neuronal excitability by oxycodone in the rat hippocampal CA3 neurons. Can J Physiol Pharmacol 99(7):737-743
34. Chiu KM, Lin TY, Lee MY, Lu CW, Wang MJ, Wang SJ*. (2021 May) Typhaneoside suppresses glutamate release through inhibition of voltage-dependent calcium entry in rat cerebrocortical nerve terminals. Chem Res Toxicol 34(5):1286-1295
35. Wang CC, Kuo JR, Wang SJ*. (2021 Mar) Fingolimod inhibits glutamate release through activation of S1P1 receptors and the G protein βγ subunit-dependent pathway in rat cerebrocortical nerve terminals. Neuropharmacology 185:108451.
36. Chang Y, Hung CF, Ko HH, Wang SJ*. (2021 Mar) Albanin A, derived from the root bark of Morus alba L., depresses glutamate release in the rat cerebrocortical nerve terminals via Ca2+/calmodulin/adenylate cyclase 1 suppression. J Med Food 24(3):209-217.
37. Lu CW, Lin TY, Pan TL, Wang PW, Chiu KM, Lee MY, Wang SJ*. (2021 Mar) Asiatic acid prevents cognitive deficits by inhibiting calpain activation and preserving synaptic and mitochondrial function in rats with kainic acid-induced seizure. Biomedicines 2021, 9(3), 284.
其他教學經驗
其他教學經驗
期間 內容
醫學系/PBL小班導師及藥理學大堂授課
護理系/藥理學
呼吸治療系/藥理學
臨心系/藥理學