學歷
學校 系所 學位
台大醫學院 藥理學研究所 博士、碩士
高雄醫學院 藥學系 學士
經歷
期間 單位 部門 職稱
輔仁大學 焯炤講座教授
輔仁大學 學術特聘教授
哈佛大學暨波士頓兒童醫院 訪問學者
輔仁大學 研發處 研發長
輔仁大學 醫學院 行政副院長
輔大附設醫院 社區醫學暨長期照護部 部長
輔仁大學 長期照護碩士學位學程 主任
輔大附設醫院 長期照護科 代理主任
輔大附設醫院 家庭醫學科 代理主任
輔仁大學 產學育成中心 主任
輔仁大學 海量資料研究中心 主任
輔仁大學 研究管理組 組長
輔仁大學 樂齡大學 主任
輔仁大學 醫學系 副教授、助理教授
高雄醫學大學 藥學系 合聘教授
高雄醫學大學 香粧品系 合聘教授
中華天然藥物學會 第十屆理事
國際跨專業長期照顧協會 理事長
台北市高雄醫學大學 藥學系校友會 理事長
高雄醫學大學 藥學院校友會 會長
國際醫療翻譯協會 副理事長
國防醫學院 藥研所 博士後研究
專長
Skinceuticals
Cardiovascular pharmacology
Natural products
學術著作
期刊論文
期間 內容
Publications from 2018 (學術期刊發表)
1. Tsai YC, Chang HH, Chou SC, Chu TW, Hsu YJ, Hsiao CY, Lo YH, Wu NL, Chang DC, Hung CF*. Evaluation of the Anti-Atopic Dermatitis Effects ofα-Boswellic Acid on Tnf-α/Ifn-γ-Stimulated HaCat Cells and DNCB-Induced BALB/c Mice. Int. J. Mol. Sci. 2022 Aug, 23(17), 9863
2. Chen KJ, Huang YL, Kuo LM, Chen YT, Hung CF, Hsieh PW. Protective role of casuarinin from Melastoma malabathricum against a mouse model of 5-fluorouracil-induced intestinal mucositis: Impact on inflammation and gut microbiota dysbiosis. Phytomedicine. 2022 Jul;101: 154092.
3. Hsiao PF, Huang YT, Lu PH, Chiu LY, Weng TH, Hung CF, Wu NL. Thioredoxin-interacting protein regulates keratinocyte differentiation: Implication of its role in psoriasis. FASEB J. 2022 May;36(5): e22313.
4. Chang JF, Kuo HL, Liu SH, Hsieh CY, Hsu CP, Hung KC, Wang TM, Wu CC, Lu KC, Lin WN, Hung CF, Ko WC. Translational Medicine in Uremic Vascular Calcification: Scavenging ROS Attenuates p-Cresyl Sulfate-Activated Caspase-1, NLRP3 Inflammasome and Eicosanoid Inflammation in Human Arterial Smooth Muscle Cells. Life (Basel). 2022 May 23;12(5):769.
5. Wang CC, Hsiao CY, Hsu YJ, Ko HH, Chang DC, Hung CF*. Anti-Inflammatory Effects of Cycloheterophyllin on Dinitrochlorobenzene-Induced Atopic Dermatitis in HaCaT Cells and BALB/c Mice. Molecules 2022 Apr 19; 27(9): 2610.
6. Ko WC, Wang SJ, Hsiao CY, Hung CT, Hsu YJ, Chang DC, Hung CF*. Pharmacological Role of Functionalized Gold Nanoparticles in Disease Applications. Molecules. 2022 Feb 25;27(5):1551.
7. Lin TK, Hung CF, Weng JR, Hsieh TY, Wang SJ. Kaempferol 3-Rhamnoside on Glutamate Release from Rat Cerebrocortical Nerve Terminals Involves P/Q-Type Ca2+ Channel and Ca2+/Calmodulin-Dependent Protein Kinase II-Dependent Pathway Suppression. Molecules 2022 Feb 16;27(4):1342.
8. Huang CC, Liu CY, Huang CJ, Hsu YC, Lien HH, Wong JU, Tai FC, Ku WH, Hung CF, Lin JT, Huang CS, Chiang HS. Deciphering Genetic Alterations of Taiwanese Patients with Pancreatic Adenocarcinoma through Targeted Sequencing. Int J Mol Sci. 2022 Jan 29;23(3):1579.
9. Yeh KC, Hung CF, Lee HL, Hsieh TY, Wang SJ. Soybean Meal Extract Preserves Memory Ability by Increasing Presynaptic Function and Modulating Gut Microbiota in Rats. Mol Neurobiol. 2022 Mar;59(3):1649-1664.
10. Lu PH, Wang JY, Chiu LY, Huang YT, Hung CF, Wu NL. Spleen tyrosine kinase regulates keratinocyte inflammasome activation and skin inflammation induced by UVB irradiation. Free Radic Biol Med. 2022 Feb 20; 180:121-133.
11. Liang IC, Ko WC, Hsu YJ, Lin YR, Chang YH, Zong XH, Lai PC, Chang DC, Hung CF*, The Anti-Inflammatory Effect of Hydrogen Gas Inhalation and Its Influence on Laser-Induced Choroidal Neovascularization in a Mouse Model of Neovascular Age-Related Macular Degeneration. Int J Mol Sci. 2021 Nov 7;22(21):12049.
12. Chiu KM, Hung YL, Wang SJ, Tsai YJ, Wu NL, Liang CW, Chang DC, Hung CF*, Anti-allergic and anti-inflammatory effects of neferine on RBL-2H3 cells. Int J Mol Sci. 2021 Oct 12;22(20):10994.
13. Chang HH, Hung CF, Chen IC, Wu PC, Liu LW, Fang CC. Long-Term Clinical Outcomes of New-Generation Drug-Eluting Stents in Coronary Artery Disease: A Real-World Observational Study. Acta Cardiol Sin. 2021 Sep;37(5):484-495.
14. Yang CC, Hung YL, Ko WC, Tsai YJ, Chang JF, Liang CW, Chang DC, Hung CF*, Effect of neferine on DNCB-induced atopic dermatitis in HaCaT Cells and BALB/c mice. Int J Mol Sci. 2021 Jul 30;22(15):8237.
15. Chang CJ, Hung YL, Chen TC, Li HJ, Lo YH, Wu NY, Chang DC, Hung CF*, Anti-proliferative and anti-migratory activities of hispidulin on human melanoma A2058 Cells. Biomolecules. 2021 Jul 16;11(7):1039.
16. Liang IC, Hsiang Y, Chang YH, Martínez AH, Hung CF*, Irisclaw intraocular lens: Anterior chamber or retropupillary implantation? A systematic review and meta-analysis. Medicina (Kaunas). 2021 Jul 30;57(8):785.
17. Yang CC, Hung YL, Li HJ, Lin YF, Wang SJ, Chang DC, Pu CM, Hung CF*, Quercetin inhibits histamine-induced calcium influx in human keratinocyte via histamine H4 receptors. Int Immunopharmacol. 2021 Jul; 96: 107620.
18. H.H. Chang, H.H. Ko, T.M. Lu, J.Y. Lin, D.C. Chang, T.W. Chu, C.F. Hung*, Inhibition of UVA Damage on Human Skin Dermis Fibroblasts by the Isoflavonoid Intermediate Deoxybenzoin-3A. Chem Res Toxicol. 2021 Apr 19;34(4):1133-1139.
19. Chiu, L. Y.; Wu, N. L.; Hung, C. F. ; Bai, P.; Dai, Y. S.; Lin, W. W., PARP-1 involves in UVB-induced inflammatory response in keratinocytes and skin injury via regulation of ROS-dependent EGFR transactivation and p38 signaling. FASEB J. 2021 Mar;35(3): e21393.
20. Y.-C. Lin, Y.-P. Fang, C.-F. Hung, H.-P. Yu, A. Alalaiwe, Z.-Y. Wu, J.-Y. Fang, Multifunctional TiO2/SBA-15 mesoporous silica hybrids loaded with organic sunscreens for skin application: the role in photoprotection and pollutant adsorption with reduced sunscreen permeation, Colloids and Surfaces B: Biointerfaces (2021) 111658.
21. Y. Chang, C.F. Hung, H.H. Ko, S.J. Wang, Albanin A, Derived from the Root Bark of Morus alba L., Depresses Glutamate Release in the Rat Cerebrocortical Nerve Terminals via Ca2+/Calmodulin/Adenylate Cyclase 1 Suppression, Journal of Medicinal Food 24(3) (2021) 209-217.
22. Z.Y. Liao, J.Y. Liou, S.C. Lin, H.F. Hung, C.M. Chang, L.C. Chen, S.K. Chua, H.M. Lo, Hung CF*, Successful bailout stenting strategy against rare spontaneous retrograde dissection of partially absorbed magnesium-based resorbable scaffold: A case report, World J Clin Cases 9(5) (2021) 1148-1155.
23. M.-H. Lin#, Hung CF #, H.-C. Sung, S.-C. Yang, H.-P. Yu, J.-Y. Fang, The Bioactivities of Resveratrol and Its Naturally Occurring Derivatives on Skin, Journal of Food and Drug Analysis 29(1) (2021) 15-38
24. Chu T, Wu NL, Hsiao CY, Li HJ, Lin TY, Ku CH, Hung CF *. An isoflavone extract from soybean cake suppresses 2,4-dinitrochlorobenzene-induced contact dermatitis. J Ethnopharmacol. 2020 Dec 5; 263:113037. (Epub 2020 May 30.)
25. Lu CW, Lin TY, Yang HC, Hung CF, Weng JR, Chang C, Wang SJ. [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol, an indole-3-carbinol derivative, inhibits glutamate release in rat cerebrocortical nerve terminals by suppressing the P/Q-type Ca2+ channels and Ca2+/calmodulin/protein kinase A pathway. Neurochem Int. 2020 Nov; 140:104845.
26. Hsu SK, Hung CF, Yang HC, Weng JR, Wang SJ. TCD, a triterpenoid isolated from wild bitter gourd, reduces synaptosomal release of glutamate and protects against kainic acid-induced neuronal death. Food Funct. 2020 Nov 18;11(11):9858-9867.
27. Yeh KC, Hung CF, Lin YF, Chang C, Pai MS, Wang SJ. Neferine, a bisbenzylisoquinoline alkaloid of Nelumbo nucifera, inhibits glutamate release in rat cerebrocortical nerve terminals through 5-HT 1A receptors. Eur J Pharmacol. 2020 Sep 19; 889:173589.
28. Liao ZY, Liang IC, Li HJ, Wu CC, Lo HM, Chang DC, Hung CF*. Chrysin Inhibits High Glucose-Induced Migration on Chorioretinal Endothelial Cells via VEGF and VEGFR Down-Regulation. Int. J. Mol. Sci. 2020 Aug; 21, 5541
29. Chang JF, Hsieh CY, Liou JC, Liu SH, Hung CF, Lu KC, Lin CC, Wu CC, Ka SM, Wen LL, Wu MS, Zheng CM, Ko WC. Scavenging Intracellular ROS Attenuates p-Cresyl Sulfate-Triggered Osteogenesis through MAPK Signaling Pathway and NF-κB Activation in Human Arterial Smooth Muscle Cells. Toxins (Basel). 2020 Jul 24;12(8): E472.
30. Chang JF, Hsieh CY, Lu KC, Chen YW, Liang SS, Lin CC, Hung CF, Liou JC, Wu MS. Therapeutic Targeting of Aristolochic Acid Induced Uremic Toxin Retention, SMAD 2/3 and JNK/ERK Pathways in Tubulointerstitial Fibrosis: Nephroprotective Role of Propolis in Chronic Kidney Disease. Toxins (Basel). 2020 Jun 2;12(6):364.
31. Wang JY1, Lu PH, Lin WW, Wei YH, Chiu LY, Chern SR, Hung CF, Wu NL. Galectin-3 regulates UVB-induced inflammation in skin. J Dermatol Sci. 2020 May;98(2):119-127.
32. Li HJ, Wu NL, Pu CM, Hsiao CY, Chang DC, Hung CF*. Chrysin alleviates IMQ-induced psoriasis-like skin inflammation and reduces the release of CCL20 and antimicrobial peptides. Scientific Reports 2020 Feb 19; 10(1):2932.
33. Wang CC, Ho YH, Hung CF, Kuo JR, Wang SJ. Xanthohumol, an active constituent from hope, affords protection against kainic acid-induced excitotoxicity in rats. Neurochem Int. Neurochem Int. 2020 Feb;133: 104629. (Epub 2019 Dec 6)
34. Chan CM, Hsiao CY, Li HJ, Fang JY, Chang DC, Hung CF* The inhibitory effects of gold nanoparticles on VEGF-A-induced cell migration in choroid-retina endothelial cells. Int J Mol Sci. 2019 Dec; 21(1): 109.
35. Wang HE, Liao YC, Hu JM, Wu WC, Chou WY, Chen YC, Chou YC, Hung CF, Tian YF, You SL, Sun CA. Correlation between kidney transplantation and colorectal cancer in hemodialysis patients: A nationwide, retrospective, population-based cohort study. BMC Cancer. 2019 Nov 16;19(1):1120.
36. Wu WT, Tsai CT, Chou YC, Ku PM, Chen YC, You SL, Hung CF, Sun CA. Cardiovascular Outcomes Associated With Clinical Use of Citalopram and Omeprazole: A Nationwide Population-Based Cohort Study. J Am Heart Assoc. 2019 Oct 15;8(20): e011607.
38. Su IC, Hung CF, Lin CN, Huang SK, Wang SJ. Cycloheterophyllin Inhibits the Release of Glutamate from Nerve Terminals of the Rat Hippocampus. Chem Res Toxicol. 2019 Aug 19;32(8):1591-1598.
39. Lu CW, Hung CF, Lin TY, Hsieh TY, Wang SJ. Allicin Inhibits Glutamate Release from Rat Cerebral Cortex Nerve Terminals Through Suppressing Ca2+ Influx and Protein Kinase C Activity. J Med Food. 2019 Jul;22(7):696-702.
40. Chen CY, Hu JM, Shen CJ, Chou YC, Tian YF, Chen YC, You SL, Hung CF, Lin TC, Hsiao CW1, Lin CY6, Sun CA. Increased incidence of colorectal cancer with obstructive sleep apnea: a nationwide population-based cohort study. Sleep Med. 2019 Mar 7; 66:15-20.
41. Alalaiwe A, Hung CF, Leu YL, Tahara K, Chen HH, Hu KY, Fang JY. The active compounds derived from Psoralea corylifolia for photochemotherapy against psoriasis-like lesions: The relationship between structure and percutaneous absorption. Eur J Pharm Sci. 2018 Nov 1;124: 114-126.
42. Hou YC, Wu CC, Liao MT, Shyu JF, Hung CF, Yen TH, Lu CL, Lu KC. Role of nutritional vitamin D in osteoporosis treatment. Clin Chim Acta. 2018 Sep;484: 179-191.
43. Lu CL, Shyu JF, Wu CC, Hung CF, Liao MT, Liu WC, Zheng CM, Hou YC, Lin YF, Lu KC. (2018, Aug). Association of Anabolic Effect of Calcitriol with Osteoclast-Derived Wnt 10b Secretion. Nutrients. 2018 Aug 25;10(9):1164.
44. Li H J, Wu N L, Lee G A, Hung CF* (2018, Apr). The Therapeutic Potential and Molecular Mechanism of Isoflavone Extract against Psoriasis. Sci Rep. 2018 Apr 20;8(1):6335. MOST 104-2320-B-030-008-MY3.
45. Zheng CM, Wu C C, Hung CF, Liao, M. T. Shyu, J. F. Hsu, Y. H. Lu, C. L. Wang, Y. H. Zheng, J. Q. Chang, T. J. Lin, Y. F. Lu, K. C. (2018, Feb). Cholecalciferol Additively ReducesSerum Parathyroid Hormone Levels in Severe Secondary Hyperparathyroidism Treated with Calcitriol and Cinacalcet among Hemodialysis Patients. Nutrients. 2018 Feb 10;10(2).
46. Hu JM, Shen CJ, Chou YC, Hung CF, Tian YF, You SL, Chen CY, Hsu CH, Hsiao CW, Lin CY, Sun CA. Risk of colorectal cancer in patients with periodontal disease severity: a nationwide, population-based cohort study. Int J Colorectal Dis. 2018 Mar;33(3):349-352.
47. Lin MH#, Hung CF#, Yang, S. C. Hung, C. F. Fang, J. Y. (2018, Jan). The Interplay Between Nanoparticles and Neutrophils. J Biomed Nanotechnol. 2018 Jan 1;14(1):66-85.
研討會論文
期間 內容
Hung CF, Chan CM, Li HJ. The inhibitory effects of gold nanoparticles on VEGF-A-induced cell migration in choroid-retina endothelial cells. PT11-07, 3-8 November, 2019, Nago, Okinawa, Japan
Wu NL, Lu PH, Lin WW, Huang DY, Gu CH, Hung CF. Spleen tyrosine kinase regulates UVB-induced inflammation in skin. The 6th Continental Congress of Dermatology. The 13th Annual Meeting of the Taiwanese Society for Investigative Dermatology. 2018. 16-18. Taipei, Taiwan. (Oral, T1)
Chiu, LY, Wu NL, Hung CF, Lin WW. PARP-1 involves in regulation of UVB-induced inflammation in skin via DNA repair and NLRP3 inflammasome activation in keratinocytes and macrophages. The 6th Continental Congress of Dermatology. The 13th Annual Meeting of the Taiwanese Society for Investigative Dermatology. 2018. 16-18. Taipei, Taiwan (P05)
Hung KL, Hung CF, Lin JT. Visiting tour of medical humanities museum for non-medical university students Taiwan Association of Medical Education 2018 Annual Meeting and Conference. 2018.11.13. NTU, Taipei, Taiwan
Hung CF. Evaluating the protective effects of nature products for barrier care. International Cosmetic-Tech Conference & Exhibition. 2018.9.14-15 Kaohsiung, Taiwan (Oral)
研究計畫
期間 主持人 計畫名稱 贊助單位 贊助金額 職稱
歷年科技部專題研究計畫:
1. 台灣天然物標靶多型免疫反應在異位皮膚炎治療與預防之研究 (110.8~113.7)(MOST110-2320-B-030 -004 -MY3)(三年期)
2. 中草藥成分及其萃取物於過敏性皮膚疾病之治療策略與應用(107.8~110.7)(MOST107-2320-B-030-003-MY3)(三年期)
3. 中草藥成分及其萃取物對發炎性皮膚疾病之治療潛力及其分子作用機轉探討 (104.8~107.7)(MOST104-2320-B-030-008-MY3 )(三年期)
4. 中草藥之類胡蘿蔔素與類黃酮成分應用在皮膚發炎及屏障損傷相關疾病之研究及機轉探討(101.8~104.7)(101-2320-B-030-005-MY3)(三年期)
5. 天然物成分對皮膚結構保護之研究(100.8~101.7)(NSC100-2320-B-030-002)
6. 傳統中草藥萃取純成份及複合配方抗皮膚及眼睛老化之探索 (97.8~100.7)(97-2320-B-030-001-MY3)(三年期)
7. 傳統中藥成份在皮膚保護與吸收之評估與應用 (95.8~97.7)(NSC 95-2320-B-030-007-MY2)(二年期)
8. 微米級和奈米級茄紅素粉末對皮膚保護功效的研究(93.8~96.7) (NSC-93-2745-B-030-005-URD,NSC-94-2745-B-030004-URD)(三年期)
9. 評估國內分離之天然物成分及其衍生物在皮膚保養之應用-經皮吸收與有效性機轉之探討(NSC 94-2320-B030-008)
10. 研究與評估類黃鹼素經皮吸收能力及護膚功效(結構與活性分析)(NSC 93-2320-B-030-014)
11. 評估並改善植物多酚化合物經皮吸收及協同功效之研究(NSC 92-2320-B-030-011)
12. 抗氧化劑及維他命經皮吸收之評估與改善(NSC 91-2320-B-030-010)
其他教學經驗
其他教學經驗
期間 內容
全人教育課程中心/化妝品科學與應用
基礎醫學研究所/老化特論/實驗藥理學
基礎醫學研究所/藥理學特論
臨床心理系/藥理學
醫學系/PBL/Tutor
醫學系/心臟血管藥理學
護理系、呼吸治療系/藥理學
護理研究所/進階心臟血管藥理學