• Faculty for Basic Medicine
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Ph.D. in The Johns Hopkins University

Human Molecular Genetics

Journal Paper
Since 2015
1: Chao WC, Lu JF, Wang JS, Chiang TH, Lin LJ, Lee YL, Chou PT. Unveiling the structural features of nonnative trimers of human superoxide dismutase 1. Biochim Biophys Acta Gen Subj. 2020 Mar;1864(3):129483. doi: 10.1016/j.bbagen.2019.129483. Epub 2019 Nov 14. PubMed PMID: 31734464.
2: Huang KC, Wang ML, Chen SJ, Kuo JC, Wang WJ, Nhi Nguyen PN, Wahlin KJ, Lu JF, Tran AA, Shi M, Chien Y, Yarmishyn AA, Tsai PH, Yang TC, Jane WN, Chang CC, Peng CH, Schlaeger TM, Chiou SH. Morphological and Molecular Defects in Human Three-Dimensional Retinal Organoid Model of X-Linked Juvenile Retinoschisis. Stem Cell Reports. 2019 Nov 12;13(5):906-923. doi: 10.1016/j.stemcr.2019.09.010. Epub 2019 Oct 24. PubMed PMID: 31668851; PubMed Central PMCID: PMC6895767.
3: Liang JS, Huang H, Wang JS, Lu JF. Phenotypic manifestations between male and female children with CDKL5 mutations. Brain Dev. 2019 Oct;41(9):783-789. doi: 10.1016/j.braindev.2019.05.003. Epub 2019 May 20. PubMed PMID: 31122804.
4: Liang, JS, Wang, JS, Lin, LJ, Yang, MT, Hung, KL, Lu, JF. Genetic Diagnosis in Children with Epilepsy and Developmental Delay/Mental Retardation Using Targeted Gene Panel Analysis. Neuropsychiatry (London) 2018 Dec 29; 8(5):1577-85
5: Chao WC, Chiang TH, Chaudhari PD, Lin LJ, Lu JF, Hong BC, Wang JS, Lin TC, Shen JY, Chou PT. The azatryptophan-based fluorescent platform for in vitro rapid screening of inhibitors disrupting IKKβ-NEMO interaction. Bioorg Chem. 2018 Dec;81:504-511. doi: 10.1016/j.bioorg.2018.09.006. Epub 2018 Sep 11. PubMed PMID: 30245232.
6: Peng CH, Huang KC, Lu HE, Syu SH, Yarmishyn AA, Lu JF, Buddhakosai W, Lin TC, Hsu CC, Hwang DK, Shen CN, Chen SJ, Chiou SH. Generation of induced pluripotent stem cells from a patient with X-linked juvenile retinoschisis. Stem Cell Res. 2018 May;29:152-156. doi: 10.1016/j.scr.2018.04.005. Epub 2018 Apr 11. Erratum in: Stem Cell Res. 2019 Jan;34:101388. PubMed PMID: 29674172.
7: Su DJ, Lu JF, Lin LJ, Liang JS, Hung KL. SCN2A mutation in an infant presenting with migrating focal seizures and infantile spasm responsive to a ketogenic diet. Brain Dev. 2018 Sep;40(8):724-727. doi: 10.1016/j.braindev.2018.03.005. Epub 2018 Apr 4. PubMed PMID: 29625812.
8: Liang JS, Lin LJ, Lin HC, Yang MT, Wang JS, Lu JF. An unusual GFAP mutation in a Taiwanese child with infantile Alexander disease. Pediatr Neonatol. 2018 Dec;59(6):624-627. doi: 10.1016/j.pedneo.2017.12.009. Epub 2017 Dec 26. PubMed PMID: 29339051.
9: Yang HC, Yang CH, Huang MY, Lu JF, Wang JS, Yeh YQ, Jeng US. Homology Modeling and Molecular Dynamics Simulation Combined with X-ray Solution Scattering Defining Protein Structures of Thromboxane and Prostacyclin Synthases. J Phys Chem B. 2017 Dec 21;121(50):11229-11240. doi: 10.1021/acs.jpcb.7b08299. Epub 2017 Dec 8. PubMed PMID: 29168638.
10: Chao WC, Lin LJ, Lu JF, Wang JS, Lin TC, Chen YH, Chen YT, Yang HC, Chou PT. Unveiling the water-associated conformational mobility in the active site of ascorbate peroxidase. Biochim Biophys Acta Gen Subj. 2018 Mar;1862(3):451-459. doi: 10.1016/j.bbagen.2017.10.022. Epub 2017 Dec 22. PubMed PMID: 29104043.
11: Liang JS, Lin LJ, Yang MT, Wang JS, Lu JF. The therapeutic implication of a novel SCN2A mutation associated early-onset epileptic encephalopathy with Rett-like features. Brain Dev. 2017 Nov;39(10):877-881. doi: 10.1016/j.braindev.2017.06.003. Epub 2017 Jul 11. PubMed PMID: 28709814.
12: Hung KL, Liang JS, Wang JS, Chen HJ, Lin LJ, Lu JF. Association of a novel GABRG2 splicing variation and a PTGS2/COX-2 single nucleotide polymorphism with Taiwanese febrile seizures. Epilepsy Res. 2017 Jan;129:1-7. doi: 10.1016/j.eplepsyres.2016.11.004. Epub 2016 Nov 14. PubMed PMID: 27871023.
13: Chen YT, Chao WC, Kuo HT, Shen JY, Chen IH, Yang HC, Wang JS, Lu JF, Cheng RP, Chou PT. Probing the polarity and water environment at the protein-peptide binding interface using tryptophan analogues. Biochem Biophys Rep. 2016 Jun 2;7:113-118. doi: 10.1016/j.bbrep.2016.05.022. eCollection 2016 Sep. PubMed PMID: 28955897; PubMed Central PMCID: PMC5613298.
14: Chao WC, Shen JY, Yang CH, Lan YK, Yuan JH, Lin LJ, Yang HC, Lu JF, Wang JS, Wee K, Chen YH, Chou PT. The In Situ Tryptophan Analogue Probes the Conformational Dynamics in Asparaginase Isozymes. Biophys J. 2016 Apr 26;110(8):1732-1743. doi: 10.1016/j.bpj.2016.03.029. PubMed PMID: 27119634; PubMed Central PMCID: PMC4850355.
15: Liu JS, Chiang TH, Wang JS, Lin LJ, Chao WC, Inbaraj BS, Lu JF, Chen BH. Induction of p53-independent growth inhibition in lung carcinoma cell A549 by gypenosides. J Cell Mol Med. 2015 Jul;19(7):1697-709. doi: 10.1111/jcmm.12546. Epub 2015 Mar 17. PubMed PMID: 25781909; PubMed Central PMCID: PMC4511366.