學歷
學校 系所 學位
台大醫學院 微生物學研究所 博士
經歷
期間 單位 部門 職稱
輔仁大學 醫學院/護理系 副教授
馬偕紀念醫院 醫研科癌症研究組 副研究員
台大醫院 肝炎中心 博士後研究員
專長
病毒學
分子生物
生物資訊
學術著作
期刊論文
期間 內容
1.Wang LJ, Mu SC, Cheng I, Chen YL, Chen BF, Jow GM. (2012) Decreased leptin concentration in neonates is associated with enhanced postnatal growth during the first year. Kaohsiung Journal of Medical Sciences (SCI).
2.Kao JH, Liu CJ, Jow GM, Chen PJ, Chen DS, Chen BF*. (2012) Fine mapping of hepatitis B virus pre-S deletion and its association with hepatocellular carcinoma. Liver International 32:1373-81(SCI).
3.Lin CM, Wang GM, Jow GM, Chen BF*. (2012) Functional analysis of hepatitis B virus pre-s deletion variants associated with hepatocellular carcinoma. Journal of Biomedical Science 19:17 (SCI).
4.Mu SC, Wang GM, Jow GM, Chen BF*. (2011) Impact of universal vaccination on intrafamilial transmission of hepatitis B virus. Journal of Medical Virology 83: 783-790 (SCI).
5.Chen BF*. (2010) Clinical Significance of Hepatitis B Virus pre-S deletion. Fu-Jen Journal of Medicine 8: 85-95.
6.Mu SC, Lin YM, Jow GM, Chen BF*. (2009) Occult hepatitis B virus infection in hepatitis B vaccinated children in Taiwan. Journal of Hepatology 50:264-272. (SCI)
7.Liu CJ, Chen BF, Chen PJ, Lai MY, Huang WL, Kao JH, Chen DS. (2006) Role of hepatitis B virus precore/core promoter mutations and serum viral load on noncirrhotic hepatocellular carcinoma: a case-control study. Journal of Infectious Diseases 194: 594-599. (SCI)
8.Liu CH, Chen BF, Chen SC, Lai MY, Kao JH, Chen DS. (2006) Selective transmission of hepatitis C virus quasi species through a needlestick accident in acute resolving hepatitis. Clinical Infectious Diseases 42: 1254-1259. (SCI).
9.Liu CJ, Chen BF, Chen PJ, Lai MY, Huang WL, Kao JH, Chen DS. (2006) Role of hepatitis B viral load and basal core promoter mutation in hepatocellular carcinoma in hepatitis B carriers. Journal of Infectious Diseases 193: 1258-1265. (SCI)
10.Chen BF, Liu CJ, Jow GM, Chen PJ, Kao JH, Chen DS. (2006) High prevalence and mapping of pre-S deletion in hepatitis B virus carriers with progressive liver diseases. Gastroenterology 130: 1153-1168. (SCI)
11.Chen BF, Tsai MC, Jow GM. (2006) Induction of calcium influx from extracellular fluid by beauvericin in human leukemia cells. Biochemical and Biophysical Research Communications 340: 134-139. (SCI)
12.Chen BF, Liu CJ, Jow GM, Chen PJ, Kao JH, Chen DS. (2006) Evolution of hepatitis B virus in an acute hepatitis B patient co-infected with genotypes B and C. Journal of General Virology 87: 39-49. (SCI)
13.Lin CL, Kao JH, Chen BF, Chen PJ, Lai MY, Chen DS. (2005) Application of hepatitis B virus genotyping and phylogenetic analysis in intrafamilial transmission of hepatitis B virus. Clinical Infectious Diseases 41: 1578-1581. (SCI).
14.Lin HI, Lee YJ, Chen BF, Tsai MC, Lu JL, Chou CJ, Jow GM. (2005) Involvement of Bcl-2 family, cytochrome c and caspase 3 in induction of apoptosis by beauvericin in human non-small cell lung cancer cells. Cancer Letters 230: 248-259.(SCI)
15.Chen BF*. (2004) Clinical significance of hepatitis B virus genotype. Fu-Jen Journal of Medicine 2:273-282.
16.Jow GM, Chou CJ, Chen BF, Tsai JH. (2004) Beauvericin induces cytotoxic effects in human acute lymphoblastic leukemia cells through cytochrome c release, caspase 3 activation: the causative role of calcium. Cancer Letters 216:165-173. (SCI)
17.Chen BF, Chen PJ, Jow GM, Sablon E, Liu CJ, Chen DS, Kao JH. (2004) High prevalence of mixed genotype infections in hepatitis B virus infected intravenous drug users. Journal of Medical Virology 74:536-542. (SCI)
18.Chen BF, Kao JH, Liu CJ, Chen DS, Chen PJ. (2004) Genotypic dominance and novel recombinations in HBV genotype B and C co-infected intravenous drug users. Journal of Medical Virology 73:13-22. (SCI)
研討會論文
期間 內容
2005年 台灣肝臟學會年度會議 講員 題目: Prevalence of pre-s deletion, precore and basal core promoter mutants in sera from hepatitis B virus carriers with hepatocellular carcinoma
2006 4th Asia-Pacific Bioinformatics Conference (APBC2006) 第四屆亞太生物資訊會議,並發表poster: Evolution of hepatitis B virus in an acute hepatitis B patient co-infected with genotypes B and C.
研究計畫
期間 主持人 計畫名稱 贊助單位 贊助金額 職稱
1.分析注射藥物毒癮者血中HBV基因型和preS基因突變株分佈的情形
2.分析同時被HBV/B和HBV/C感染的靜脈注射藥物者血中HBV演化的情形
3.分析HBV基因型C型病毒感染之靜脈注射藥物毒癮者血中病毒突變株分佈的情形
4.分析HBV基因型 B型病毒感染之靜脈注射藥物毒癮者血中病毒突變株分佈的情形
5.B型肝炎病毒 pre-S deletion 和 precore/core 突變與肝癌形成關連性之分析
6.B型肝炎病毒之subgenotype和pre-S突變株與肝癌形成關連性之探討
7.利用microarray 的方法分析B型肝炎病毒pre-S缺陷(Deletion)突變株可能之致癌成因
8.利用反轉錄病毒載體以建立一持續表現B型肝炎病毒pre-S缺陷(Deletion)突變株之肝細胞,進而分析這些突變株之致癌性形成關連性之分析
其他教學經驗
其他教學經驗
期間 內容
公衛系/生物技術概論
公衛系/微生物與免疫學
公衛系/微生物與免疫學實驗
全人中心/病毒與人生
呼吸治療學系/微生物與免疫學
呼吸治療學系/微生物與免疫學實驗
醫學系/PBL課程之小班導師
醫學系/PBL課程之授課老師
醫學系/PBL課程之微生物資源老師
醫學系/基礎醫學實驗
護理系/微生物與免疫學